Phytochemical Profiling, Antioxidant and Antimicrobial Potentials of Ethanol and Ethyl Acetate Extracts of <i>Chamaenerion latifolium</i> L.

• প্রধান লেখক: Akmaral Kozhantayeva (Author), Nurgul Tursynova (Author), Ainagul Kolpek (Author), Yelaman Aibuldinov (Author), Arailym Tursynova (Author), Togzhan Mashan (Author), Zhazira Mukazhanova (Author), Manshuk Ibrayeva (Author), Aizhan Zeinuldina (Author), Aisha Nurlybayeva (Author), Zhanar Iskakova (Author), Yerbolat Tashenov (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2024-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

সংক্ষিপ্ত

The study investigates the phytochemical profile, antioxidant capacity, and antimicrobial activities of ethanol (ChL-EtOH) and ethyl acetate (ChL-EtOAc) extracts from <i>Chamaenerion latifolium</i> L. (ChL) harvested in Kazakhstan. The ChL-EtOH extract exhibited higher total phenolic (267.48 ± 3.44 mg GAE/g DE) and flavonoid content (24.18 ± 1.06 mg QE/g DE) compared to ChL-EtOAc. HPLC-UV-ESI/MS identified key phenolic acids and flavonoids, including gallic acid, chlorogenic acid, and quercetin 3-glucoside. FT-IR analysis confirmed the presence of characteristic functional groups. Antioxidant assays revealed strong DPPH scavenging and FRAP activities, with ChL-EtOH showing superior results (IC₅₀ = 21.31 ± 0.65 μg/mL and 18.13 ± 0.15 μg/mL, respectively). Additionally, ChL-EtOH displayed notable antimicrobial efficacy against Gram-positive and Gram-negative bacteria, as well as the fungal strain <i>Candida albicans</i>. These findings suggest that ethanol extraction is more efficient for isolating bioactive compounds from ChL, underscoring its potential for pharmaceutical and nutraceutical applications.

উপাদানের বিবরণ

10.3390/ph17080996
1424-8247