Ancestry and frequency of genetic variants in the general population are confounders in the characterization of germline variants linked to cancer
Abstract Background Pediatric high-grade gliomas (pHGGs) are incurable malignant brain cancers. Clear somatic genetic drivers are difficult to identify in the majority of cases. We hypothesized that this may be due to the existence of germline variants that influence tumor etiology and/or progressio...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
BMC,
2020-05-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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