Synthesis and Antimicrobial activity 2-chloro-6-methylquinoline Hydrazone derivatives
<div>A series of 2-chloro-6-methylquinoline hydrazones (3a-o) were synthesized by the condensation of substituted acyl</div><div>hydrazines, semicarbazide, thiosemicarbazide and INH with 2-chloro-3-formyl-6-methylquinoline in absolute alcohol.</div><div>The structures o...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Wolters Kluwer Medknow Publications,
2009-12-01T00:00:00Z.
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| Summary: | <div>A series of 2-chloro-6-methylquinoline hydrazones (3a-o) were synthesized by the condensation of substituted acyl</div><div>hydrazines, semicarbazide, thiosemicarbazide and INH with 2-chloro-3-formyl-6-methylquinoline in absolute alcohol.</div><div>The structures of compounds were established using spectral data and elemental analysis. All the compounds were</div><div>evaluated for their antibacterial activity against Escherichia coli (NCTC, 10418), Staphylococcus aureus (NCTC, 65710)</div><div>and Pseudomonas aeruginosa (NCTC, 10662). Compounds were also tested for antifungal activity aganist Aspergillus</div><div>niger (MTCC, 281), Aspergillus flavus (MTCC, 277), Monascus purpureus (MTCC, 369) and Penicillium citrinum</div><div>(NCIM, 768) by cup-plate method.</div> |
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| Item Description: | 0975-7406 |