N-Acetyldopamine Dimer Attenuates DSS-Induced Ulcerative Colitis by Suppressing NF-κB and MAPK Pathways

• Main Authors: Li-Jun Huang (Author), Yu-Mei Wang (Author), Lei-Qiang Gong (Author), Chao Hu (Author), Yu Gui (Author), Chen Zhang (Author), Xue Tan (Author), Xian-Kuo Yu (Author), Yi-Le Liao (Author), Yan Luo (Author), Yu-Qin Tang (Author), Yi-Fei Dai (Author), Yun Deng (Author), Dong Wang (Author), Da-le Guo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ulcerative Colitis (UC) is a major form of chronic inflammatory bowel disease of the colonic mucosa and exhibits progressive morbidity. There is still a substantial need of small molecules with greater efficacy and safety for UC treatment. Here, we report a N-acetyldopamine dimer (NADD) elucidated (...