Therapeutic potential of topical administration of acriflavine against hypoxia-inducible factors for corneal fibrosis
Transdifferentiation of keratocytes into fibroblasts or further into myofibroblasts, which produced denser and more disorganized extracellular matrix, is the major cause of corneal fibrosis and scarring, leading to corneal blindness. TGF-β1 is the critical cytokine for the myofibroblast's trans...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2022-10-01T00:00:00Z.
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