Over-Expressed GATA-1_S, the Short Isoform of the Hematopoietic Transcriptional Factor GATA-1, Inhibits Ferroptosis in K562 Myeloid Leukemia Cells by Preventing Lipid Peroxidation

• Main Authors: Silvia Trombetti (Author), Nunzia Iaccarino (Author), Patrizia Riccio (Author), Raffaele Sessa (Author), Rosa Catapano (Author), Marcella Salvatore (Author), Stelina Luka (Author), Sergio de Nicola (Author), Paola Izzo (Author), Sante Roperto (Author), Pasqualino Maddalena (Author), Antonio Randazzo (Author), Michela Grosso (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferroptosis is a recently recognized form of regulated cell death involving lipid peroxidation. Glutathione peroxidase 4 (GPX4) plays a central role in the regulation of ferroptosis through the suppression of lipid peroxidation generation. Connections have been reported between ferroptosis, lipid me...