pH and reduction dual-responsive micelles based on novel polyurethanes with detachable poly(2-ethyl-2-oxazoline) shell for controlled release of doxorubicin
We describe a biodegradable amphiphilic polyurethane (PU) with disulfide bonds in the main chain [PEtOz-b-PU(SS)-b-PEtOz]. This multi-block PU was synthesized using poly (ε-caprolactone) diol (PCL-SS-PCL) and poly (2-ethyl-2-oxazoline) (PEtOz-OH) as soft segments, and bis (2-isocyanatoethyl) disulfi...
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Main Authors: | Leran Bu (Author), Hena Zhang (Author), Kang Xu (Author), Baixiang Du (Author), Caihong Zhu (Author), Yuling Li (Author) |
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Format: | Book |
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Taylor & Francis Group,
2019-01-01T00:00:00Z.
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