Prevalence and Factors Associated with Prosthetic Joint Infections in Patients with <i>Staphylococcus aureus</i> Bacteraemia: A 7-Year Retrospective Study
Background: <i>Staphylococcus aureus</i> is the main cause of haematogenous prosthetic joint infections (PJI). We aimed to describe the prevalence and factors associated with PJI in patients with documented <i>S. aureus</i> bacteraemia. Methods: Adult patients with <i>S...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Book |
| Published: |
MDPI AG,
2022-09-01T00:00:00Z.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Background: <i>Staphylococcus aureus</i> is the main cause of haematogenous prosthetic joint infections (PJI). We aimed to describe the prevalence and factors associated with PJI in patients with documented <i>S. aureus</i> bacteraemia. Methods: Adult patients with <i>S. aureus</i> bacteraemia and presence of prosthetic joint hospitalized in Lausanne University Hospital during a seven-year period (2015-2021) were included. Results: Among 135 patients with <i>S. aureus</i> bacteraemia and prosthetic joints, 38 (28%) had PJI. Multivariate analysis revealed that the presence of PJI was associated with knee arthroplasty (<i>P</i> 0.029; aOR 3.00, 95% CI 1.12-8.05), prior arthroplasty revision (<i>P</i> 0.034; aOR 3.59, 95% CI 1.10-11.74), community-acquired bacteraemia (<i>P</i> 0.005; aOR 4.74, 95% CI 1.61-14.01) and age < 70 years (<i>P</i> 0.007; aOR 9.39, 95% CI 1.84-47.85). Conclusions: PJI was common among patients with documented <i>S. aureus</i> bacteraemia. PJI was associated with characteristics of the prosthesis, such as prior arthroplasty revisions and knee prosthesis. |
|---|---|
| Item Description: | 10.3390/antibiotics11101323 2079-6382 |