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Mechanistic PBPK Modelling to Predict the Advantage of the Salt Form of a Drug When Dosed with Acid Reducing Agents

Acid reducing agents (ARAs) reduce the dissolution rate of weakly basic drugs in the stomach potentially leading to lower bioavailability. Formulating the API as a rapidly dissolving salt is one strategy employed to reduce the impact of ARAs on dissolution of such drugs. In the present work, a model...

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Xehetasun bibliografikoak
Egile Nagusiak:	Siri Kalyan Chirumamilla (Egilea), Venkatesh Teja Banala (Egilea), Masoud Jamei (Egilea), David B. Turner (Egilea)
Formatua:	Liburua
Argitaratua:	MDPI AG, 2021-07-01T00:00:00Z.
Gaiak:	article
Sarrera elektronikoa:	Connect to this object online.
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

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