Signet-ring cells in the skin: a case of late-onset cutaneous metastasis of gastric carcinoma and a brief review of histological approach

Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both...

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Bibliographic Details
Main Authors: Özgür Gündüz (Author), Mehmet Can Emeksiz (Author), Pınar Atasoy (Author), Mehtap Kıdır (Author), Selim Yalçın (Author), Serkan Demirkan (Author)
Format: Book
Published: PAGEPress Publications, 2017-01-01T00:00:00Z.
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Summary:Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both situations, they are associated with poor prognosis, which can partly be attributed to underdiagnosis. In this paper, a case of relapsing gastric adenocarcinoma, which manifested itself as asymptomatic cutaneous papules and nodules on a patient's head and neck, is reported and histopathological approach to the cutaneous lesions containing signet-ring cell is briefly reviewed.
Item Description:2036-7392
2036-7406
10.4081/dr.2016.6819