Signet-ring cells in the skin: a case of late-onset cutaneous metastasis of gastric carcinoma and a brief review of histological approach

Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both...

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Main Authors: Özgür Gündüz (Author), Mehmet Can Emeksiz (Author), Pınar Atasoy (Author), Mehtap Kıdır (Author), Selim Yalçın (Author), Serkan Demirkan (Author)
Format: Book
Published: PAGEPress Publications, 2017-01-01T00:00:00Z.
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100 1 0 |a Özgür Gündüz  |e author 
700 1 0 |a Mehmet Can Emeksiz  |e author 
700 1 0 |a Pınar Atasoy  |e author 
700 1 0 |a Mehtap Kıdır  |e author 
700 1 0 |a Selim Yalçın  |e author 
700 1 0 |a Serkan Demirkan  |e author 
245 0 0 |a Signet-ring cells in the skin: a case of late-onset cutaneous metastasis of gastric carcinoma and a brief review of histological approach 
260 |b PAGEPress Publications,   |c 2017-01-01T00:00:00Z. 
500 |a 2036-7392 
500 |a 2036-7406 
500 |a 10.4081/dr.2016.6819 
520 |a Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both situations, they are associated with poor prognosis, which can partly be attributed to underdiagnosis. In this paper, a case of relapsing gastric adenocarcinoma, which manifested itself as asymptomatic cutaneous papules and nodules on a patient's head and neck, is reported and histopathological approach to the cutaneous lesions containing signet-ring cell is briefly reviewed. 
546 |a EN 
690 |a Signet-ring cell, metastatic skin cancer, immunohistochemistry 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Dermatology Reports, Vol 8, Iss 1 (2017) 
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787 0 |n https://doaj.org/toc/2036-7392 
787 0 |n https://doaj.org/toc/2036-7406 
856 4 1 |u https://doaj.org/article/322e16a0eb084ffbab2d1e70b2e3a9c5  |z Connect to this object online.