Effects of Dietary Nitrate Supplementation on Performance during Single and Repeated Bouts of Short-Duration High-Intensity Exercise: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
Inorganic nitrate (NO<sub>3</sub><sup>−</sup>) has emerged as a potential ergogenic aid over the last couple of decades. While recent systematic reviews and meta-analyses have suggested some small positive effects of NO<sub>3</sub><sup>−</sup> suppleme...
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MDPI AG,
2023-05-01T00:00:00Z.
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|---|---|---|---|
| 001 | doaj_324c1b231d134e44b6e4cf9f34a7beea | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Nehal S. Alsharif |e author |
| 700 | 1 | 0 | |a Tom Clifford |e author |
| 700 | 1 | 0 | |a Abrar Alhebshi |e author |
| 700 | 1 | 0 | |a Samantha N. Rowland |e author |
| 700 | 1 | 0 | |a Stephen J. Bailey |e author |
| 245 | 0 | 0 | |a Effects of Dietary Nitrate Supplementation on Performance during Single and Repeated Bouts of Short-Duration High-Intensity Exercise: A Systematic Review and Meta-Analysis of Randomised Controlled Trials |
| 260 | |b MDPI AG, |c 2023-05-01T00:00:00Z. | ||
| 500 | |a 10.3390/antiox12061194 | ||
| 500 | |a 2076-3921 | ||
| 520 | |a Inorganic nitrate (NO<sub>3</sub><sup>−</sup>) has emerged as a potential ergogenic aid over the last couple of decades. While recent systematic reviews and meta-analyses have suggested some small positive effects of NO<sub>3</sub><sup>−</sup> supplementation on performance across a range of exercise tasks, the effect of NO<sub>3</sub><sup>−</sup> supplementation on performance during single and repeated bouts of short-duration, high-intensity exercise is unclear. This review was conducted following PRISMA guidelines. MEDLINE and SPORTDiscus were searched from inception to January 2023. A paired analysis model for cross-over trials was incorporated to perform a random effects meta-analysis for each performance outcome and to generate standardized mean differences (SMD) between the NO<sub>3</sub><sup>−</sup> and placebo supplementation conditions. The systematic review and meta-analysis included 27 and 23 studies, respectively. Time to reach peak power (SMD: 0.75, <i>p</i> = 0.02), mean power output (SMD: 0.20, <i>p</i> = 0.02), and total distance covered in the Yo-Yo intermittent recovery level 1 test (SMD: 0.17, <i>p</i> < 0.0001) were all improved after NO<sub>3</sub><sup>−</sup> supplementation. Dietary NO<sub>3</sub><sup>−</sup> supplementation had small positive effects on some performance outcomes during single and repeated bouts of high-intensity exercise. Therefore, athletes competing in sports requiring single or repeated bouts of high-intensity exercise may benefit from NO<sub>3</sub><sup>−</sup> supplementation. | ||
| 546 | |a EN | ||
| 690 | |a nitric oxide | ||
| 690 | |a beetroot | ||
| 690 | |a exercise performance | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Antioxidants, Vol 12, Iss 6, p 1194 (2023) | |
| 787 | 0 | |n https://www.mdpi.com/2076-3921/12/6/1194 | |
| 787 | 0 | |n https://doaj.org/toc/2076-3921 | |
| 856 | 4 | 1 | |u https://doaj.org/article/324c1b231d134e44b6e4cf9f34a7beea |z Connect to this object online. |