Levodopa acts centrally to induce an antinociceptive action against colonic distension through activation of D2 dopamine receptors and the orexinergic system in the brain in conscious rats

• Egile Nagusiak: Toshikatsu Okumura (Egilea), Tsukasa Nozu (Egilea), Shima Kumei (Egilea), Kaoru Takakusaki (Egilea), Saori Miyagishi (Egilea), Masumi Ohhira (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2016-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Levodopa possesses antinociceptive actions against several somatic pain conditions. However, we do not know at this moment whether levodopa is also effective to visceral pain. The present study was therefore performed to clarify whether levodopa is effective to visceral pain and its mechanisms. Visc...