Therapeutic Targeting of TLR4 for Inflammation, Infection, and Cancer: A Perspective for Disaccharide Lipid A Mimetics
The Toll-like receptor 4 (TLR4) signaling pathway plays a central role in the prompt defense against infectious challenge and provides immediate response to Gram-negative bacterial infection. The TLR4/MD-2 complex can sense and respond to various pathogen-associated molecular patterns (PAMPs) with b...
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Main Authors: | Holger Heine (Author), Alla Zamyatina (Author) |
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Format: | Book |
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MDPI AG,
2022-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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