Influence of Renal Function and Age on the Pharmacokinetics of Levofloxacin in Patients with Bone and Joint Infections

• Main Authors: Gauthier Eloy (Author), David Lebeaux (Author), Manon Launay (Author), Marie-Paule Fer (Author), Eliane Billaud (Author), Emmanuel Douez (Author), Jean-Luc Mainardi (Author), Benjamin Bouyer (Author), Vincent Jullien (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite its efficacy and toxicity being exposure-related, levofloxacin pharmacokinetics in patients with bone and joint infections has been poorly described to date, so the possible need for a dose adjustment is unknown in this population. A prospective population pharmacokinetic study was conducted...