Tadalafil, a Long-Acting Inhibitor of PDE5, Improves Pulmonary Hemodynamics and Survival Rate of Monocrotaline-Induced Pulmonary Artery Hypertension in Rats

• প্রধান লেখক: Fusae Sawamura (লেখক), Masami Kato (লেখক), Kazuhisa Fujita (লেখক), Takahiro Nakazawa (লেখক), Anthony Beardsworth (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2009-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The aim of this study was to assess the effect of tadalafil (0.5, 2.5, and 10 mg/kg per day) on the progression of pulmonary arterial hypertension (PAH) in early treatment and on the survival rate in late treatment on the monocrotaline (MCT)-induced PAH rat model. Tadalafil was administered once dai...