pH-Responsive polymer boosts cytosolic siRNA release for retinal neovascularization therapy

• Main Authors: Shuai Guo (Author), Chunhui Li (Author), Changrong Wang (Author), Xiaowen Cao (Author), Xinyue Liu (Author), Xing-Jie Liang (Author), Yuanyu Huang (Author), Yuhua Weng (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Small interfering RNA (siRNA) has a promising future in the treatment of ocular diseases due to its high efficiency, specificity, and low toxicity in inhibiting the expression of target genes and proteins. However, due to the unique anatomical structure of the eye and various barriers, delivering nu...