The Core-Targeted RRM2 Gene of Berberine Hydrochloride Promotes Breast Cancer Cell Migration and Invasion via the Epithelial-Mesenchymal Transition

• المؤلفون الرئيسيون: Jiaming He (مؤلف), Qiang Wei (مؤلف), Rong Jiang (مؤلف), Tiankuo Luan (مؤلف), Shuang He (مؤلف), Ruijin Lu (مؤلف), Hang Xu (مؤلف), Jianhua Ran (مؤلف), Jing Li (مؤلف), Dilong Chen (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Berberine hydrochloride (BBR) could inhibit the proliferation, migration, and invasion of various cancer cells. As the only enzyme for the de novo synthesis of ribonucleotides, RRM2 is closely related to the development of tumorigenesis. However, not much is currently known about the functional role...