The phenomena of balanced effect between α-globin gene and of β-globin gene

• Main Authors: Liangying Zhong (Author), Xin Gan (Author), Lingling Xu (Author), Chujia Liang (Author), Yingjun Xie (Author), Wenbin Lin (Author), Peisong Chen (Author), Min Liu (Author)
• Format: Book
• Published: BMC, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Thalassemias (TM) are the most common autosomal recessive disorders in Southeast Asian countries. Both α- and β-thalassemia lead to a decrease or absence of globin chains. The most serious of the thalassemia syndromes is thalassemia major which is characterized by a transfusion d...