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Ilexsaponin A1 Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease by Regulating Bile Acid Metabolism in Mice

Bile acid (BA) metabolism is an attractive therapeutic target in nonalcoholic fatty liver disease (NAFLD). We aimed to investigate the effect of ilexsaponin A1 (IsA), a major bioactive ingredient of Ilex, on high-fat diet (HFD)-induced NAFLD in mice with a focus on BA homeostasis. Male C57BL/6J mice...

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Main Authors: Wen-wen Zhao (Author), Meng Xiao (Author), Xia Wu (Author), Xiu-wei Li (Author), Xiao-xi Li (Author), Ting Zhao (Author), Lan Yu (Author), Xiao-qing Chen (Author)
Format: Book
Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
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