Evidence for the Gut Microbiota Short-Chain Fatty Acids as Key Pathophysiological Molecules Improving Diabetes

• Auteurs principaux: Alessandra Puddu (Auteur), Roberta Sanguineti (Auteur), Fabrizio Montecucco (Auteur), Giorgio Luciano Viviani (Auteur)
• Format: Livre
• Publié: Hindawi Limited, 2014-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

In type 2 diabetes, hyperglycemia, insulin resistance, increased inflammation, and oxidative stress were shown to be associated with the progressive deterioration of beta-cell function and mass. Short-chain fatty acids (SCFAs) are organic fatty acids produced in the distal gut by bacterial fermentat...