XLMR in MRX families 29, 32, 33 and 38 results from the dup24 mutation in the ARX (Aristaless related homeobox) gene

• Main Authors: MacMillan Andrée (Author), Macgregor David (Author), Holinski-Feder Elke (Author), Mangelsdorf Marie (Author), Finnis Merran (Author), Cason A Lauren (Author), Stepp Monica L (Author), Holden Jeanette JA (Author), Gecz Jozef (Author), Stevenson Roger E (Author), Schwartz Charles E (Author)
• Formato: Livro
• Publicado em: BMC, 2005-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>X-linked mental retardation (XLMR) is the leading cause of mental retardation in males. Mutations in the ARX gene in Xp22.1 have been found in numerous families with both nonsyndromic and syndromic XLMR. The most frequent mutation in...