Health-related quality of life and associated factors in Chinese menstrual migraine patients: a cross-sectional study

• Main Authors: Wenxiu Luo (Author), Xing Cao (Author), Jiayu Zhao (Author), Jiaming Yang (Author), Yu Cen (Author), Jinlong He (Author), Jing Luo (Author), Yunling Zhong (Author), Ying Luo (Author), Xinyue Wang (Author), Liqiu Yang (Author), Xingyu Feng (Author), Xiaoqing Pang (Author), Jiazhu Zhang (Author), Jiaming Luo (Author)
• Format: Book
• Published: BMC, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Abstract Background Menstrual migraine is a particular form of migraine with a significant impact on the quality of life for women afflicted. Presently, no study has reported the quality of life in menstrual migraine patients. This work aims to assess the health-related quality of life and identify its associated factors among Chinese menstrual migraine patients. Methods The cross-sectional study group consisted of 109 patients with menstrual migraine, and the control group consisted of 397 female patients with non-menstrual migraine. In total, 506 patients completed questionnaires for demographic and clinical information, the Self-rating Idea of Suicide Scale, the Hamilton Depression Scale, the Hamilton Anxiety Scale, the Headache Impact Test-6, the Perceived Social Support Scale, the Pittsburgh Sleep Quality Index. Health-related quality of life was measured using the 36-Item Short Form Survey. Results Compared with non-menstrual migraine patients, five dimensions of health-related quality of life were all found to be significantly impaired in menstrual migraine patients. Headache frequency (ß = − 0.218, P = 0.014), the impact of headache on daily life (ß = − 0.270, P = 0.002), depression symptoms (ß = − 0.345, P < 0.001) were significantly associated with physical component summary, depression symptoms (ß = − 0.379, P < 0.001), social support (ß = 0.270, P < 0.001), suicidal ideation (ß = − 0.344, P < 0.001) were closely related to mental component summary. Conclusion Menstrual migraine patients had a significantly poorer health-related quality of life in many domains than non-menstrual migraine patients. Headache frequency, the impact of headache on daily life, depression symptoms, social support, and suicidal ideation were significantly associated with health-related quality of life in menstrual migraine patients. Trial registration: ChiCTR1800014343. This study was registered prospectively on 7 January 2018 at Chinese Clinical Trial registry. http://www.chictr.org.cn/showproj.aspx?proj=24526

Item Description

10.1186/s12905-022-01760-8
1472-6874