Exploring the Mechanism of Sempervirine Inhibiting Glioblastoma Invasion Based on Network Pharmacology and Bioinformatics

• Main Authors: Bingqiang Zhang (Author), Wenyi Wang (Author), Yu Song (Author), Huixian Chen (Author), Xinxin Lin (Author), Jingjing Chen (Author), Ying Chen (Author), Jinfang Huang (Author), Desen Li (Author), Shuisheng Wu (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>Background</b>: Invasion is an important characteristic of the malignancy of glioblastoma (GBM) and a significant prognostic factor. Sempervirine (SPV), a yohimbine-type alkaloid, has been proven to inhibit GBM cells proliferation in previous research and found to have a potential eff...