Integrative analysis of eQTL and GWAS summary statistics reveals transcriptomic alteration in Alzheimer brains

• Main Authors: Pradeep Varathan (Author), Priyanka Gorijala (Author), Tanner Jacobson (Author), Danai Chasioti (Author), Kwangsik Nho (Author), Shannon L. Risacher (Author), Andrew J. Saykin (Author), Jingwen Yan (Author)
• Format: Book
• Published: BMC, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Large-scale genome-wide association studies have successfully identified many genetic variants significantly associated with Alzheimer's disease (AD), such as rs429358, rs11038106, rs723804, rs13591776, and more. The next key step is to understand the function of these SNPs...