Leveraging the power of supercritical fluid chromatography for eco-conscious solutions in pharmaceutical analysis

Initially employed primarily at a preparative scale for enantiomer separation of chiral drug candidates, Supercritical Fluid Chromatography (SFC) is nowadays extensively used in the analytical mode. Recent advances in SFC separation science have emphasized its potential for modern and environmentall...

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Main Authors: Krmar Jovana (Author), Svrkota Bojana (Author), Obradović Darija (Author), Vlatković Vladimir (Author), Lazović Saša (Author), Otašević Biljana (Author)
Format: Book
Published: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2024-01-01T00:00:00Z.
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100 1 0 |a Krmar Jovana  |e author 
700 1 0 |a Svrkota Bojana  |e author 
700 1 0 |a Obradović Darija  |e author 
700 1 0 |a Vlatković Vladimir  |e author 
700 1 0 |a Lazović Saša  |e author 
700 1 0 |a Otašević Biljana  |e author 
245 0 0 |a Leveraging the power of supercritical fluid chromatography for eco-conscious solutions in pharmaceutical analysis 
260 |b Pharmaceutical Association of Serbia, Belgrade, Serbia,   |c 2024-01-01T00:00:00Z. 
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500 |a 2217-8767 
500 |a 10.5937/arhfarm74-49565 
520 |a Initially employed primarily at a preparative scale for enantiomer separation of chiral drug candidates, Supercritical Fluid Chromatography (SFC) is nowadays extensively used in the analytical mode. Recent advances in SFC separation science have emphasized its potential for modern and environmentally friendly pharmaceutical analysis. The aim of this review is to provide a deeper insight into the main fundamental and practical aspects of the SFC technique in order to familiarize readers with its versatile nature and efficiency in creating sustainable chromatographic solutions. All considerations are made primarily in the context of the most widely used mode of operation - achiral SFC. In addition, recent applications of this promising technique are presented at the end of the article to further promote its use in pharmaceutical analytical practice. 
546 |a SR 
690 |a supercritical fluid chromatography 
690 |a pharmaceuticals 
690 |a achiral separations 
690 |a environmental friendliness 
690 |a Pharmacy and materia medica 
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786 0 |n Arhiv za farmaciju, Vol 74, Iss 2, Pp 133-159 (2024) 
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