Inhibition of protein tyrosine phosphatase (PTP1B) and α-glucosidase by geranylated flavonoids from Paulownia tomentosa

• Auteurs principaux: Yeong Hun Song (Auteur), Zia Uddin (Auteur), Young Min Jin (Auteur), Zuopeng Li (Auteur), Marcus John Curtis-Long (Auteur), Kwang Dong Kim (Auteur), Jung Keun Cho (Auteur), Ki Hun Park (Auteur)
• Format: Livre
• Publié: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase are important targets to treat obesity and diabetes, due to their deep correlation with insulin and leptin signalling, and glucose regulation. The methanol extract of Paulownia tomentosa fruits showed potent inhibition against both enzymes. P...