The role of IDH1/2 mutations in the pathogenesis of secondary glioblastomas

• Autor Principal: Eduardo Cambruzzi (Author)
• Formato: Libro
• Publicado: Sociedade Brasileira de Patologia Clínica, 2017-10-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

ABSTRACT Diffuse astrocytoma and glioblastoma (GBM) constitute a group of diffusely infiltrating astrocytic neoplasms, which more commonly arise in cerebral hemispheres of adults. The prevalence of malignant transformation of diffuse astrocytoma to anaplastic astrocytoma and GBM varies from 40% to 7...