PIWI silencing mechanism involving the retrotransposon nimbus orchestrates resistance to infection with Schistosoma mansoni in the snail vector, Biomphalaria glabrata.

• Main Authors: Michael Smith (Author), Swara Yadav (Author), Olayemi G Fagunloye (Author), Nana Adjoa Pels (Author), Daniel A Horton (Author), Nashwah Alsultan (Author), Andrea Borns (Author), Carolyn Cousin (Author), Freddie Dixon (Author), Victoria H Mann (Author), Clarence Lee (Author), Paul J Brindley (Author), Najib M El-Sayed (Author), Joanna M Bridger (Author), Matty Knight (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Schistosomiasis remains widespread in many regions despite efforts at its elimination. By examining changes in the transcriptome at the host-pathogen interface in the snail Biomphalaria glabrata and the blood fluke Schistosoma mansoni, we previously demonstrated that a...