Association between rs2275913 single‐nucleotide polymorphism of the interleukin‐17A gene and perioperative analgesic use in cosmetic orthognathic surgery

• Main Authors: Seii Ohka (Author), Daisuke Nishizawa (Author), Junko Hasegawa (Author), Kaori Takahashi (Author), Kyoko Nakayama (Author), Yuko Ebata (Author), Ken‐ichi Fukuda (Author), Kazutaka Ikeda (Author)
• Format: Book
• Published: Wiley, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aim Interleukin‐17A (IL‐17A) plays an essential role in tissue inflammation by inducing proinflammatory cytokine and chemokine production and is related to innate immune reactions. IL‐17A also contributes to neuroinflammation, neuropathic pain, and mechanical hypersensitivity after peripher...