A Computational Synaptic Antibody Characterization Tool for Array Tomography

• Main Authors: Anish K. Simhal (Author), Belvin Gong (Author), James S. Trimmer (Author), Richard J. Weinberg (Author), Stephen J Smith (Author), Guillermo Sapiro (Author), Kristina D. Micheva (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Application-specific validation of antibodies is a critical prerequisite for their successful use. Here we introduce an automated framework for characterization and screening of antibodies against synaptic molecules for high-resolution immunofluorescence array tomography (AT). The proposed Synaptic...