Nitrous Oxide sedation for intra-articular injection in juvenile idiopathic arthritis

• Main Authors: Harel Liora (Author), Press Joseph (Author), Tauber Tsivia (Author), Rothschild Michal (Author), Chapnick Gil (Author), Uziel Yosef (Author), Hashkes Philip J (Author)
• Format: Book
• Published: BMC, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

<p>Abstract</p> <p>Background</p> <p>Intra-articular corticosteroid injection in juvenile idiopathic arthritis (JIA) is often associated with anxiety and pain. Recent reports advocate the use of nitrous oxide (NO), a volatile gas with analgesic, anxiolytic and sedative properties.</p> <p>Objective</p> <p>To prospectively evaluate the effectiveness and safety of NO analgesia for intra-articular corticosteroid injection in JIA, and to assess patients and staff satisfaction with the treatment.</p> <p>Methods</p> <p>NO was administered to JIA patients scheduled for joint injection. The patient, parent, physician and nurse completed visual-analog scores (VAS) (0-10) for pain, and a 5-point satisfaction scale. Change in heart rate (HR) during the procedure was recorded in order to examine physiologic response to pain and stress. Patient's behavior and adverse reactions were recorded.</p> <p>Results</p> <p>54 procedures (72 joints) were performed, 41 females, 13 males; 39 Jewish, 13 Arab; mean age was 12.2 ± 4.7 year. The median VAS pain score for patients, parents, physicians and nurses was 3. The HR increased ≥ 15% in 10 patients. They had higher VAS scores as evaluated by the staff. The median satisfaction level of the parents and staff was 3.0 and 5.0 respectively. Adverse reactions were mild.</p> <p>Conclusion</p> <p>NO provides effective and safe sedation for JIA children undergoing intra-articular injections.</p>

Item Description

10.1186/1546-0096-6-1
1546-0096