Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG adjuvants

• Main Authors: Sakshi Bajoria (Author), Kawaljit Kaur (Author), Ozan S. Kumru (Author), Greta Van Slyke (Author), Jennifer Doering (Author), Hayley Novak (Author), Sergio A. Rodriguez Aponte (Author), Neil C. Dalvie (Author), Christopher A. Naranjo (Author), Ryan S. Johnston (Author), Judith Maxwell Silverman (Author), Harry Kleanthous (Author), J. Christopher Love (Author), Nicholas J. Mantis (Author), Sangeeta B. Joshi (Author), David B. Volkin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Low-cost, refrigerator-stable COVID-19 vaccines will facilitate global access and improve vaccine coverage in low- and middle-income countries. To this end, subunit-based approaches targeting the receptor-binding domain (RBD) of SARS-CoV-2 Spike protein remain attractive. Antibodies against RBD neut...