Diet-Intestinal Microbiota Axis in Osteoarthritis: A Possible Role
Intestinal microbiota is highly involved in host physiology and pathology through activity of the microbiome and its metabolic products. Osteoarthritis (OA) is a common form of arthritis characterized by articular cartilage destruction and osteophyte formation. Although various person-level risk fac...
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| Main Authors: | , , , |
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| Formato: | Libro |
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Hindawi Limited,
2016-01-01T00:00:00Z.
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| Acceso en liña: | Connect to this object online. |
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| Summary: | Intestinal microbiota is highly involved in host physiology and pathology through activity of the microbiome and its metabolic products. Osteoarthritis (OA) is a common form of arthritis characterized by articular cartilage destruction and osteophyte formation. Although various person-level risk factors, such as age, sex, and obesity, have been proposed for the pathogenesis of OA, the underlying links between these person-level factors and OA are still enigmatic. Based on the current understanding in the crosstalk between intestinal microbiota and these risk factors, intestinal microbiota could be considered as a major hidden risk factor that provides a unifying mechanism to explain the involvement of these person-level risk factors in OA. |
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| descrición da copia: | 0962-9351 1466-1861 10.1155/2016/3495173 |