Improved Aptamers for the Diagnosis and Potential Treatment of HER2-Positive Cancer

Aptamers provide a potential source of alternative targeting molecules for existing antibody diagnostics and therapeutics. In this work, we selected novel DNA aptamers targeting the HER2 receptor by an adherent whole-cell SELEX approach. Individual aptamers were identified by next generation sequenc...

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Bibliographic Details
Main Authors: Marlies Gijs (Author), Gregory Penner (Author), Garth B. Blackler (Author), Nathalie R.E.N. Impens (Author), Sarah Baatout (Author), André Luxen (Author), An M. Aerts (Author)
Format: Book
Published: MDPI AG, 2016-05-01T00:00:00Z.
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