BRAF L485-P490 deletion mutant metastatic melanoma sensitive to BRAF and MEK inhibition: A case report and literature review
Background: The combination therapy of BRAF inhibitors (BRAFis) and MEK inhibitors (MEKis) has been approved as a first-line treatment for metastatic melanoma with BRAF V600 mutants. Recently, BRAF mutations have been divided into three subtypes based on biochemical and signaling characteristics. Un...
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Main Authors: | Simeng Zhang (Author), Zichang Yang (Author), Yu Cheng (Author), Xiaoyu Guo (Author), Chang Liu (Author), Shuo Wang (Author), Lingyun Zhang (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2023-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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