An LC-MS/MS method for the simultaneous determination of 18 antibacterial drugs in human plasma and its application in therapeutic drug monitoring

• Main Authors: Wei Lu (Author), Meng Pan (Author), Hongqin Ke (Author), Jun Liang (Author), Wenbin Liang (Author), Ping Yu (Author), Penghua Zhang (Author), Qibin Wang (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Fag: article
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Antimicrobial resistance (AMR) is a major threat to global health due to the wide use of antibacterial drugs. Multiple studies show that the pharmacokinetic/pharmacodynamic (PK/PD) studies of antibiotics are an approach to prevent/delay AMR. The pharmacokinetic parameters of antibiotics are the basi...