A FtsZ Inhibitor That Can Utilize Siderophore-Ferric Iron Uptake Transporter Systems for Activity against Gram-Negative Bacterial Pathogens

The global threat of multidrug-resistant Gram-negative bacterial pathogens necessitates the development of new and effective antibiotics. FtsZ is an essential and highly conserved cytoskeletal protein that is an appealing antibacterial target for new antimicrobial therapeutics. However, the effectiv...

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Main Authors: Eric J. Bryan (Author), Qi Qiao (Author), Yuxuan Wang (Author), Jacques Y. Roberge (Author), Edmond J. LaVoie (Author), Daniel S. Pilch (Author)
Format: Book
Published: MDPI AG, 2024-02-01T00:00:00Z.
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