SIRT2 as a therapeutic target for age-related disorders

• Những tác giả chính: RIta eMachado de Oliveira (Tác giả), Jana eSarkander (Tác giả), Aleksey G. Kazantsev (Tác giả), Tiago F Outeiro (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2012-05-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Sirtuin proteins are conserved regulators of aging that have recently emerged as important modifiers of several diseases which commonly occur later in life, such as cancer, diabetes, cardiovascular and neurodegenerative diseases. In mammals, there are seven sirtuins (SIRT1-7), which display diversit...