<i>Anaplasma phagocytophilum</i> Encephalitis: A Case Report and Literature Review of Neurologic Manifestations of Anaplasmosis
<i>Anaplasma phagocytophilum</i> is an obligate intracellular, Gram-negative pathogen, causative agent of Human Granulocytic Anaplasmosis (HGA). HGA usually manifests as a non-specific febrile illness, accompanied by evidence of leucopenia, thrombocytopenia, and an alteration in liver en...
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| Main Authors: | , , , , , |
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| Format: | Book |
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MDPI AG,
2023-06-01T00:00:00Z.
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| Summary: | <i>Anaplasma phagocytophilum</i> is an obligate intracellular, Gram-negative pathogen, causative agent of Human Granulocytic Anaplasmosis (HGA). HGA usually manifests as a non-specific febrile illness, accompanied by evidence of leucopenia, thrombocytopenia, and an alteration in liver enzymes. Neurologic manifestations of anaplasmosis are rare and rarely reported. We describe a 62-year-old man who developed encephalitis due to an <i>Anaplasma phagocytophilum</i> infection. The patient favorably responded to intravenous doxycycline and recovered without neurological sequela. In the tick endemic area, clinicians should have a high index of suspicion for tick-borne diseases in patients presenting with neurological deficits. A prompt diagnosis and treatment lead to improvements in morbidity and mortality. |
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| Item Description: | 10.3390/idr15040035 2036-7449 |