Cells expressing PAX8 are the main source of homeostatic regeneration of adult mouse endometrial epithelium and give rise to serous endometrial carcinoma

• Main Authors: Dah-Jiun Fu (Author), Andrea J. De Micheli (Author), Mallikarjun Bidarimath (Author), Lora H. Ellenson (Author), Benjamin D. Cosgrove (Author), Andrea Flesken-Nikitin (Author), Alexander Yu. Nikitin (Author)
• Format: Book
• Published: The Company of Biologists, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Humans and mice have cyclical regeneration of the endometrial epithelium. It is expected that such regeneration is ensured by tissue stem cells, but their location and hierarchy remain debatable. A number of recent studies have suggested the presence of stem cells in the mouse endometrial epithelium...