Co-administration of herbal inhibitors of P-glycoprotein with renal drugs enhance their bioavailability- In silico approach
Introduction: Multidrug resistance (MDR) is primarily associated with reduced intracellular drug accumulation owing to overexpression of p-glycoprotein, an active efflux transporter. Competitive inhibition or allosteric modulation of p-glycoprotein may alter the pharmacokinetics of the drugs that se...
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| Format: | Book |
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Shahrekord University of Medical Sciences,
2023-04-01T00:00:00Z.
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