Salvianolate Ameliorates Osteopenia and Improves Bone Quality in Prednisone-Treated Rheumatoid Arthritis Rats by Regulating RANKL/RANK/OPG Signaling

• Main Authors: Xiang Gao (Author), Qingyun Wu (Author), Xinle Zhang (Author), Jia Tian (Author), Dahong Liang (Author), Yalin Min (Author), Jiaqi Lu (Author), Xuemei Zhang (Author), Liao Cui (Author), Bilian Xu (Author), Yanzhi Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rheumatoid arthritis (RA) is closely associated with periarticular osteopenia and leads to a high risk of generalized osteoporosis. Although glucocorticoid (GC) treatment ameliorates joint degradation and manages inflammation in RA, GC application may induce further bone quality deterioration in RA...