Tablet Disintegration and Dispersion under In Vivo-like Hydrodynamic Conditions

• Main Authors: Jan Lenz (Author), Frederik Fuest (Author), Jan Henrik Finke (Author), Heike Bunjes (Author), Arno Kwade (Author), Michael Juhnke (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Disintegration and dispersion are functional properties of tablets relevant for the desired API release. The standard disintegration test (SDT) described in different pharmacopoeias provides only limited information on these complex processes. It is considered not to be comparable to the biorelevant...