Scanning Sildenafil Citrate Solubility in Hydrotropic Solutions
Background: Sildenafil citrate (SC) is a selective phosphodiesterase-5 inhibitor with low aqueous solubility (4.1 mg/mL in water), resulting in only 40% bioavailability after oral administration. SC is classified as class II by the Biopharmaceutical Drug Classification System. Hydrotropic agents are...
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University of Mosul,
2023-12-01T00:00:00Z.
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