Progress and prospects of long noncoding RNAs in lipid homeostasis

Background: Long noncoding RNAs (lncRNAs) are a novel group of universally present, non-coding RNAs (>200 nt) that are increasingly recognized as key regulators of many physiological and pathological processes. Scope of review: Recent publications have shown that lncRNAs influence lipid homeostas...

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Main Author: Zheng Chen (Author)
Format: Book
Published: Elsevier, 2016-03-01T00:00:00Z.
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100 1 0 |a Zheng Chen  |e author 
245 0 0 |a Progress and prospects of long noncoding RNAs in lipid homeostasis 
260 |b Elsevier,   |c 2016-03-01T00:00:00Z. 
500 |a 2212-8778 
500 |a 10.1016/j.molmet.2015.12.003 
520 |a Background: Long noncoding RNAs (lncRNAs) are a novel group of universally present, non-coding RNAs (>200 nt) that are increasingly recognized as key regulators of many physiological and pathological processes. Scope of review: Recent publications have shown that lncRNAs influence lipid homeostasis by controlling lipid metabolism in the liver and by regulating adipogenesis. lncRNAs control lipid metabolism-related gene expression by either base-pairing with RNA and DNA or by binding to proteins. Major conclusions: The recent advances and future prospects in understanding the roles of lncRNAs in lipid homeostasis are discussed. Keywords: lncRNA, Liver, Lipid metabolism, Adipose tissue, Adipogenesis 
546 |a EN 
690 |a Internal medicine 
690 |a RC31-1245 
655 7 |a article  |2 local 
786 0 |n Molecular Metabolism, Vol 5, Iss 3, Pp 164-170 (2016) 
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856 4 1 |u https://doaj.org/article/386b8fce86b843b7b32d2570e80ba5ec  |z Connect to this object online.