Enhanced inflammasome activation and reduced sphingosine-1 phosphate S1P signalling in a respiratory mucoobstructive disease model
Abstract Background Inflammasomes and sphingosine-1-phosphate (S1P) signalling are increasingly subject to intensive research in human diseases. We hypothesize that in respiratory muco-obstructive diseases, mucus obstruction enhances NLRP3 inflammasome activation and dysregulated S1P signalling. Met...
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Main Authors: | Hai B. Tran (Author), Matthew G. Macowan (Author), Adrian Abdo (Author), Martin Donnelley (Author), David Parsons (Author), Sandra Hodge (Author) |
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Format: | Book |
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BMC,
2020-04-01T00:00:00Z.
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