Evaluation of the Pharmacological Profile of Ramosetron, a Novel Therapeutic Agent for Irritable Bowel Syndrome

• Prif Awduron: Takuya Hirata (Awdur), Yoshihiro Keto (Awdur), Toshiyuki Funatsu (Awdur), Shinobu Akuzawa (Awdur), Masao Sasamata (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2007-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

We examined the pharmacological profile of ramosetron, a 5-HT3-receptor antagonist for irritable bowel syndrome with diarrhea, comparing it with those of other 5-HT3-receptor antagonists, alosetron and cilansetron, and the anti-diarrheal agent loperamide. Ramosetron showed high affinity for cloned h...