Evaluation of the Pharmacological Profile of Ramosetron, a Novel Therapeutic Agent for Irritable Bowel Syndrome

• Κύριοι συγγραφείς: Takuya Hirata (Συγγραφέας), Yoshihiro Keto (Συγγραφέας), Toshiyuki Funatsu (Συγγραφέας), Shinobu Akuzawa (Συγγραφέας), Masao Sasamata (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2007-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

We examined the pharmacological profile of ramosetron, a 5-HT3-receptor antagonist for irritable bowel syndrome with diarrhea, comparing it with those of other 5-HT3-receptor antagonists, alosetron and cilansetron, and the anti-diarrheal agent loperamide. Ramosetron showed high affinity for cloned h...