Evaluation of the Pharmacological Profile of Ramosetron, a Novel Therapeutic Agent for Irritable Bowel Syndrome

• Egile Nagusiak: Takuya Hirata (Egilea), Yoshihiro Keto (Egilea), Toshiyuki Funatsu (Egilea), Shinobu Akuzawa (Egilea), Masao Sasamata (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2007-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

We examined the pharmacological profile of ramosetron, a 5-HT3-receptor antagonist for irritable bowel syndrome with diarrhea, comparing it with those of other 5-HT3-receptor antagonists, alosetron and cilansetron, and the anti-diarrheal agent loperamide. Ramosetron showed high affinity for cloned h...